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Arul M Chinnaiyan Selected Research

Enhancer of Zeste Homolog 2 Protein

1/2019Polycomb group proteins EZH2 and EED directly regulate androgen receptor in advanced prostate cancer.
10/2018Epigenetic Reprogramming with Antisense Oligonucleotides Enhances the Effectiveness of Androgen Receptor Inhibition in Castration-Resistant Prostate Cancer.
12/2008Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer.
5/2003Multiplex biomarker approach for determining risk of prostate-specific antigen-defined recurrence of prostate cancer.
10/2002The polycomb group protein EZH2 is involved in progression of prostate cancer.

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Arul M Chinnaiyan Research Topics

Disease

246Neoplasms (Cancer)
03/2022 - 01/2002
212Prostatic Neoplasms (Prostate Cancer)
01/2022 - 04/2002
32Neoplasm Metastasis (Metastasis)
01/2022 - 09/2002
29Breast Neoplasms (Breast Cancer)
01/2021 - 01/2002
21Carcinoma (Carcinomatosis)
04/2021 - 01/2003
16Carcinogenesis
03/2022 - 01/2003
14Disease Progression
01/2020 - 07/2003
11Adenocarcinoma
01/2020 - 01/2003
10Lung Neoplasms (Lung Cancer)
07/2020 - 04/2007
8Renal Cell Carcinoma (Grawitz Tumor)
01/2021 - 07/2002
8Prostatic Intraepithelial Neoplasia
08/2012 - 04/2002
6Leukemia
02/2020 - 09/2009
5Urinary Bladder Neoplasms (Bladder Cancer)
01/2022 - 05/2009
5Glioblastoma (Glioblastoma Multiforme)
10/2020 - 06/2003
5Adenocarcinoma of Lung
01/2017 - 04/2007
5Melanoma (Melanoma, Malignant)
08/2013 - 07/2002
5Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
09/2009 - 02/2005
4Glioma (Gliomas)
10/2021 - 11/2016
3Merkel Cell Carcinoma
01/2022 - 09/2017
3Brain Neoplasms (Brain Tumor)
10/2021 - 10/2017
3Lymphoma (Lymphomas)
01/2021 - 07/2002
3Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2021 - 01/2013
3Squamous Cell Carcinoma of Head and Neck
01/2021 - 11/2011
3Tuberous Sclerosis (Bourneville's Disease)
05/2020 - 10/2018
37 Hereditary Prostate Cancer
01/2017 - 03/2012
3Ewing Sarcoma (Sarcoma, Ewing)
09/2014 - 04/2012

Drug/Important Bio-Agent (IBA)

78Proteins (Proteins, Gene)FDA Link
03/2022 - 04/2002
70Biomarkers (Surrogate Marker)IBA
01/2022 - 04/2002
59RNA (Ribonucleic Acid)IBA
01/2022 - 11/2002
42AndrogensIBA
01/2021 - 06/2004
39DNA (Deoxyribonucleic Acid)IBA
06/2021 - 01/2002
30Androgen Receptors (Androgen Receptor)IBA
01/2022 - 06/2005
28Prostate-Specific Antigen (Semenogelase)IBA
07/2021 - 05/2003
25Hormones (Hormone)IBA
01/2021 - 09/2002
22Biological ProductsIBA
12/2017 - 09/2002
20Transcription Factors (Transcription Factor)IBA
01/2022 - 06/2005
18Messenger RNA (mRNA)IBA
01/2021 - 04/2002
17Long Noncoding RNAIBA
01/2018 - 07/2011
14Proto-Oncogene Proteins c-etsIBA
12/2016 - 10/2005
14Complementary DNA (cDNA)IBA
06/2011 - 08/2002
12Pharmaceutical PreparationsIBA
01/2021 - 04/2002
11ChromatinIBA
01/2022 - 08/2007
11Phosphotransferases (Kinase)IBA
01/2019 - 01/2003
10Kazal Pancreatic Trypsin InhibitorIBA
01/2022 - 02/2008
10AntigensIBA
01/2022 - 12/2002
9MicroRNAs (MicroRNA)IBA
01/2016 - 01/2010
9alpha-methylacyl-CoA racemaseIBA
06/2005 - 07/2002
8Serine Proteases (Serine Protease)IBA
01/2021 - 06/2008
8Estrogen ReceptorsIBA
01/2021 - 12/2005
7EnzymesIBA
01/2016 - 04/2002
6enzalutamideIBA
01/2022 - 01/2016
6AntibodiesIBA
01/2018 - 12/2002
6Estrogens (Estrogen)FDA Link
11/2016 - 01/2006
6AutoantibodiesIBA
11/2008 - 05/2005
5Histones (Histone)IBA
10/2021 - 02/2012
5Enhancer of Zeste Homolog 2 ProteinIBA
01/2019 - 10/2002
5Polycomb-Group ProteinsIBA
01/2019 - 10/2002
5ErbB Receptors (EGF Receptor)IBA
04/2015 - 01/2004
5Tumor Biomarkers (Tumor Markers)IBA
11/2014 - 07/2002
5Peptides (Polypeptides)IBA
10/2014 - 09/2005
4Protein Isoforms (Isoforms)IBA
01/2022 - 02/2005
4Tumor Viral Antigens (Large T Antigen)IBA
01/2022 - 09/2008
4purineIBA
01/2022 - 09/2015
4Progesterone Receptors (Progesterone Receptor)IBA
01/2021 - 12/2005
4Succinate Dehydrogenase (Fumarate Reductase)IBA
05/2020 - 06/2017
4Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
01/2019 - 05/2011
4ElementsIBA
01/2019 - 04/2004
4Phenobarbital (Luminal)FDA Link
01/2019 - 05/2012
4Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
11/2017 - 09/2004
4LigandsIBA
10/2017 - 10/2004
4Sarcosine (Methylglycine)IBA
01/2017 - 02/2009
4Glycine (Aminoacetic Acid)FDA LinkGeneric
01/2017 - 02/2009
4ProteomeIBA
01/2013 - 12/2003
4Fatty Acids (Saturated Fatty Acids)IBA
11/2011 - 03/2004
45' Untranslated Regions (5' UTR)IBA
11/2009 - 10/2005
4Neoplasm Antigens (Tumor Antigens)IBA
11/2008 - 06/2004
4Cadherins (E-Cadherin)IBA
04/2008 - 01/2003
3Immune Checkpoint InhibitorsIBA
01/2022 - 01/2021
3Programmed Cell Death 1 ReceptorIBA
01/2021 - 01/2018
3Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2021 - 04/2006
3Tyrosine Kinase InhibitorsIBA
01/2021 - 09/2004
3Glutamic Acid (Glutamate)FDA Link
12/2019 - 03/2008
3PlatinumIBA
11/2019 - 01/2017
3B7-H1 AntigenIBA
10/2018 - 10/2017
3Aurora Kinase AIBA
01/2018 - 11/2011
3Poly(ADP-ribose) Polymerase InhibitorsIBA
01/2018 - 10/2015
3olaparibIBA
01/2018 - 10/2015
3Amino AcidsFDA Link
01/2017 - 02/2009
3Choline (Choline Chloride)IBA
01/2017 - 11/2011
3Indicators and Reagents (Reagents)IBA
11/2016 - 01/2008
3Untranslated RNA (Noncoding RNA)IBA
03/2016 - 02/2008
3Glutamine (L-Glutamine)FDA Link
03/2015 - 06/2005
3Histone MethyltransferasesIBA
12/2013 - 12/2008

Therapy/Procedure

75Therapeutics
01/2022 - 04/2002
41Castration
01/2022 - 07/2010
23Prostatectomy (Retropubic Prostatectomy)
01/2022 - 05/2003
9Precision Medicine
09/2021 - 05/2013
8Radiotherapy
10/2021 - 10/2002
7Immunotherapy
12/2021 - 09/2008
7Drug Therapy (Chemotherapy)
10/2021 - 09/2004